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1

Recognition of Endogenous Nucleic Acids by the Innate Immune System

Roers, Axel, Hiller, Björn, Hornung, Veit

Journal:

Year:

2016

Language:

english

File:

PDF, 1.71 MB

english, 2016

2

Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells

Anne Krug, Simon Rothenfusser, Veit Hornung, Bernd Jahrsdörfer, Susan Blackwell, Zuhair K. Ballas, Stefan Endres, Arthur M. Krieg, Gunther Hartmann

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 179 KB

english, 2001

3

A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes

Schmid-Burgk, Jonathan L, Schmidt, Tobias, Kaiser, Vera, Höning, Klara, Hornung, Veit

Journal:

Nature Biotechnology

Year:

2012

Language:

english

File:

PDF, 1.20 MB

english, 2012

4

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Ablasser, Andrea, Goldeck, Marion, Cavlar, Taner, Deimling, Tobias, Witte, Gregor, Röhl, Ingo, Hopfner, Karl-Peter, Ludwig, Janos, Hornung, Veit

Journal:

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

5

NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR

Kainulainen, Markus, Lau, Simone, Samuel, Charles E., Hornung, Veit, Weber, Friedemann, Schultz-Cherry, S.

Journal:

Journal of Virology

Year:

2016

Language:

english

File:

PDF, 1.38 MB

english, 2016

6

Frequently used bioinformatics tools overestimate the damaging effect of allelic variants

Andersen, Line Lykke, Terczyńska-Dyla, Ewa, Mørk, Nanna, Scavenius, Carsten, Enghild, Jan J., Höning, Klara, Hornung, Veit, Christiansen, Mette, Mogensen, Trine H., Hartmann, Rune

Journal:

Genes and Immunity

Year:

2017

Language:

english

File:

PDF, 1.11 MB

english, 2017

7

DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer

Paludan, Søren R., Reinert, Line S., Hornung, Veit

Journal:

Nature Reviews Immunology

Year:

2019

Language:

english

File:

PDF, 1.90 MB

english, 2019

8

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

Anne Krug, Andreas Towarowski, Stefanie Britsch, Simon Rothenfusser, Veit Hornung, Robert Bals, Thomas Giese, Hartmut Engelmann, Stefan Endres, Arthur M. Krieg, Gunther Hartmann

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 259 KB

english, 2001

9

Distinct CpG oligonucleotide sequences activate human γ δ T cells via interferon-α/-β

Simon Rothenfusser, Veit Hornung, Anne Krug, Andreas Towarowski, Arthur M. Krieg, Stefan Endres, Gunther Hartmann

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

10

CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells

Anja Marschner, Simon Rothenfusser, Veit Hornung, Domenik Prell, Anne Krug, Miren Kerkmann, Daniela Wellisch, Hendrik Poeck, Andreas Greinacher, Thomas Giese, Stefan Endres, Gunther Hartmann

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 329 KB

english, 2005

11

Viral 5′-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses

Ramanjaneyulu Allam, Rahul D. Pawar, Onkar P. Kulkarni, Veit Hornung, Gunter Hartmann, Stephan Segerer, Shizuo Akira, Stefan Endres, Hans-Joachim Anders

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 524 KB

english, 2008

12

Cover Picture: Eur. J. Immunol. 12/08

Ramanjaneyulu Allam, Rahul D. Pawar, Onkar P. Kulkarni, Veit Hornung, Gunter Hartmann, Stephan Segerer, Shizuo Akira, Stefan Endres, Hans-Joachim Anders

Journal:

European Journal of Immunology

Year:

2008

File:

PDF, 180 KB

2008

13

Critical functions of priming and lysosomal damage for NLRP3 activation

Veit Hornung, Eicke Latz

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 166 KB

english, 2010

14

Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome

Sarah Kim, Franz Bauernfeind, Andrea Ablasser, Gunther Hartmann, Katherine A. Fitzgerald, Eicke Latz, Veit Hornung

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 244 KB

english, 2010

15

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

Martin Schlee, Andreas Roth, Veit Hornung, Cristina Amparo Hagmann, Vera Wimmenauer, Winfried Barchet, Christoph Coch, Markus Janke, Aleksandra Mihailovic, Greg Wardle, Stefan Juranek, Hiroki Kato, Ta

Journal:

Year:

2009

Language:

english

File:

PDF, 1.12 MB

english, 2009

16

Inflammasomes: current understanding and open questions

Franz Bauernfeind, Andrea Ablasser, Eva Bartok, Sarah Kim, Jonathan Schmid-Burgk, Taner Cavlar, Veit Hornung

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 637 KB

english, 2011

17

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Hornung, Veit, Ablasser, Andrea, Charrel-Dennis, Marie, Bauernfeind, Franz, Horvath, Gabor, Caffrey, Daniel. R., Latz, Eicke, Fitzgerald, Katherine A.

Journal:

Year:

2009

Language:

english

File:

PDF, 868 KB

english, 2009

18

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Hornung, Veit, Bauernfeind, Franz, Halle, Annett, Samstad, Eivind O, Kono, Hajime, Rock, Kenneth L, Fitzgerald, Katherine A, Latz, Eicke

Journal:

Nature Immunology

Year:

2008

Language:

english

File:

PDF, 687 KB

english, 2008

19

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Halle, Annett, Hornung, Veit, Petzold, Gabor C, Stewart, Cameron R, Monks, Brian G, Reinheckel, Thomas, Fitzgerald, Katherine A, Latz, Eicke, Moore, Kathryn J, Golenbock, Douglas T

Journal:

Nature Immunology

Year:

2008

Language:

english

File:

PDF, 804 KB

english, 2008

20

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

Ablasser, Andrea, Bauernfeind, Franz, Hartmann, Gunther, Latz, Eicke, Fitzgerald, Katherine A, Hornung, Veit

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 500 KB

english, 2009

21

'Toll2008' outgrows its name

Sirois, Cherilyn M, Hornung, Veit, Latz, Eicke

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 430 KB

english, 2009

22

TLR2 joins the interferon gang

Bauernfeind, Franz, Hornung, Veit

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 336 KB

english, 2009

23

Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7

Hornung, Veit, Guenthner-Biller, Margit, Bourquin, Carole, Ablasser, Andrea, Schlee, Martin, Uematsu, Satoshi, Noronha, Anne, Manoharan, Muthiah, Akira, Shizuo, de Fougerolles, Antonin

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 485 KB

english, 2005

24

Intracellular DNA recognition

Hornung, Veit, Latz, Eicke

Journal:

Nature Reviews Immunology

Year:

2010

Language:

english

File:

PDF, 484 KB

english, 2010

25

Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells

Winter, Meike, Beer, Hans-Dietmar, Hornung, Veit, Krämer, Ursula, Schins, Roel P. F., Förster, Irmgard

Journal:

Year:

2011

Language:

english

File:

PDF, 885 KB

english, 2011

26

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils

Arun K. Mankan, Therese Dau, Dieter Jenne, Veit Hornung

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 208 KB

english, 2012

27

Critical role of nucleotide-binding oligomerization domain-like receptor 3 in vascular repair

Sebastian Schlaweck, Sebastian Zimmer, Rafael Struck, Eva Bartok, Nikos Werner, Franz Bauernfeind, Eicke Latz, Georg Nickenig, Veit Hornung, Alexander Ghanem

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 517 KB

english, 2011

28

PS2-028. A non-redundant role of the NLRP3/ASC/Caspase-1 axis for L-1β processing in neutrophils

Arun K Mankan, Veit Hornung

Journal:

Year:

2011

Language:

english

File:

PDF, 133 KB

english, 2011

29

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

Tengchuan Jin, Andrew Perry, Jiansheng Jiang, Patrick Smith, James A. Curry, Leonie Unterholzner, Zhaozhao Jiang, Gabor Horvath, Vijay A. Rathinam, Ricky W. Johnstone, Veit Hornung, Eicke Latz, Andrew

Journal:

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

30

iGLuc: a luciferase-based inflammasome and protease activity reporter

Bartok, Eva, Bauernfeind, Franz, Khaminets, Maria G, Jakobs, Christopher, Monks, Brian, Fitzgerald, Katherine A, Latz, Eicke, Hornung, Veit

Journal:

Year:

2013

Language:

english

File:

PDF, 1.57 MB

english, 2013

31

Retroviral Danger from Within: TLR7 Is in Control

Mankan, Arun K., Hornung, Veit

Journal:

Year:

2012

Language:

english

File:

PDF, 300 KB

english, 2012

32

NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-LIKE RECEPTOR 3 IS CRITICAL IN VASCULAR REPAIR

Alexander Ghanem, Sebastian Schlaweck, Sebastian Zimmer, Eicke Latz, Nikos Werner, Veit Hornung, Georg Nickenig

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 91 KB

english, 2012

33

Nucleic acid driven sterile inflammation

Ablasser, Andrea, Hertrich, Carola, Waßermann, Ruth, Hornung, Veit

Journal:

Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 350 KB

english, 2013

34

Species-specific detection of the antiviral small-molecule compound CMA by STING

Cavlar, Taner, Deimling, Tobias, Ablasser, Andrea, Hopfner, Karl-Peter, Hornung, Veit

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 990 KB

english, 2013

35

Induction of type I IFNs by intracellular DNA-sensing pathways

Cavlar, Taner, Ablasser, Andrea, Hornung, Veit

Journal:

Immunology & Cell Biology

Year:

2012

Language:

english

File:

PDF, 540 KB

english, 2012

36

Structural mechanism of cytosolic DNA sensing by cGAS

Civril, Filiz, Deimling, Tobias, de Oliveira Mann, Carina C., Ablasser, Andrea, Moldt, Manuela, Witte, Gregor, Hornung, Veit, Hopfner, Karl-Peter

Journal:

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

37

Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation

Yin, Qian, Sester, David P., Tian, Yuan, Hsiao, Yu-Shan, Lu, Alvin, Cridland, Jasmyn A., Sagulenko, Vitaliya, Thygesen, Sara J., Choubey, Divaker, Hornung, Veit, Walz, Thomas, Stacey, Katryn J., Wu, H

Journal:

Year:

2013

Language:

english

File:

PDF, 3.43 MB

english, 2013

38

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

Ablasser, Andrea, Schmid-Burgk, Jonathan L., Hemmerling, Inga, Horvath, Gabor L., Schmidt, Tobias, Latz, Eicke, Hornung, Veit

Journal:

Year:

2013

Language:

english

File:

PDF, 3.30 MB

english, 2013

39

Postoperative Ileus Involves Interleukin-1 Receptor Signaling in Enteric Glia

Stoffels, Burkhard, Hupa, Kristof Johannes, Snoek, Susanne A., van Bree, Sjoerd, Stein, Kathy, Schwandt, Timo, Vilz, Tim O., Lysson, Mariola, Veer, Cornelis van't, Kummer, Markus P., Hornung, Veit, Ka

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 2.25 MB

english, 2014

40

85

Gad, Hans Henrik, Ibsen, Mikkel S., Andersen, Line L., Hornung, Veit, Sarka, Saumendra N., Hartmann, Rune

Journal:

Year:

2013

Language:

english

File:

PDF, 43 KB

english, 2013

41

OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids

Hornung, Veit, Hartmann, Rune, Ablasser, Andrea, Hopfner, Karl-Peter

Journal:

Nature Reviews Immunology

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

42

Where, in antiviral defense, does IFIT1 fit?

Ablasser, Andrea, Hornung, Veit

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 8.90 MB

english, 2011

43

OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines

Schmid-Burgk, Jonathan L., Schmidt, Tobias, Gaidt, Moritz M., Pelka, Karin, Latz, Eicke, Ebert, Thomas S., Hornung, Veit

Journal:

Genome Research

Year:

2014

Language:

english

File:

PDF, 652 KB

english, 2014

44

DNA sensing unchained

Ablasser, Andrea, Hornung, Veit

Journal:

Year:

2013

Language:

english

File:

PDF, 316 KB

english, 2013

45

146

Pelka, Karin, Phulphagar, Kshiti, Zimmermann, Jana, Schmid-Burgk, Jonathan, Schmidt, Tobias, Stahl, Rainer, Casanova, Jean-Laurent, Meissner, Felix, Hornung, Veit, Hoening, Stefan, Latz, Eicke

Journal:

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

46

Of inflammasomes and pathogens - sensing of microbes by the inflammasome

Bauernfeind, Franz, Hornung, Veit

Journal:

EMBO Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 894 KB

english, 2013

47

SnapShot: Nucleic Acid Immune Sensors, Part 1

Journal:

Year:

2014

Language:

english

File:

PDF, 638 KB

english, 2014

48

Self-priming determines high type I IFN production by plasmacytoid dendritic cells

Kim, Sarah, Kaiser, Vera, Beier, Esther, Bechheim, Matthias, Guenthner-Biller, Margit, Ablasser, Andrea, Berger, Michael, Endres, Stefan, Hartmann, Gunther, Hornung, Veit

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

49

SnapShot: Nucleic Acid Immune Sensors, Part 2

Journal:

Year:

2014

Language:

english

File:

PDF, 431 KB

english, 2014

50

Control of Hepatitis C Virus Replication in Mouse Liver-Derived Cells by MAVS-Dependent Production of Type I and Type III Interferons

Anggakusuma,, Frentzen, Anne, Gürlevik, Engin, Yuan, Qinggong, Steinmann, Eike, Ott, Michael, Staeheli, Peter, Schmid-Burgk, Jonathan, Schmidt, Tobias, Hornung, Veit, Kuehnel, Florian, Pietschmann, T

Journal:

Journal of Virology

Year:

2015

File:

PDF, 2.23 MB

2015